Opening Day 2025 Mlb Dates. Fans can look forward to a full slate of matchups as 28 of the 30 mlb clubs. The 14 games on opening day will feature four divisional matchups and four interleague contests.
The season will begin on the road on friday, april 4th in tulsa while the home portion of the schedule starts on tuesday, april 8th as the naturals take on the frisco. Complete mlb opening day information for 2024 including schedule, pitchers, teams, times, dates and how to watch.